Role of m6A methylation in post-transcriptional regulation and prostate cancer disease progression
m6A methylation of mRNAs can alter RNA stability, protein translation efficiency, and patterns of alternative splicing. The aim of the project is to investigate the frequency of m6A in prostate cancer and its functional consequences for the progression of the disease. It is the first study to examine how prostate cancer utilises this alternative molecular mechanism to regulate gene and protein expression. It will provide valuable fundamental research that will contribute to a better understanding of the molecular functioning of prostate cancer.